Endocrine Abstracts

Introduction and Backgrounds: Myxedema coma is a severe life threatening form of decompensated hypothyroidism which is associated with a high mortality rate. Infections and discontinuation of thyroid supplements are the major precipitating factors. It’s characterized by a decreased mental status, hypothermia, bradycardia, hypotension, and hypoventilation. Very few cases of Myxedema coma have been reported till date, actual prevalence is unclear with the estimated incidenc...

Introduction: Impetigo herpetiformis is a rare dermatological disorder, mimicking generalized pustular psoriasis. It is characterized by a generalized erythema-pustular eruption accompanied by fever. Its etiopathogenesis is poorly coded but triggers have been identified such as hypocalcemia in more than half of cases and pregnancy. We report a case of severe hypocalcemia secondary to hypoparathyroidism revealed by impetigo herpetiformis.Case report: Fort...

Introduction: Somatotropic adenomas are classically a source of hypersecretion of GH and consequently of IGF1 responsible for the clinical signs of acromegaly. Rarely, these adenomas remain ‘silent’, without any obvious clinical manifestation. They can then be detected on the basis of a routine determination of growth hormone under oral glucose tolerance test (GH/OGTT) and insulin growth factor 1 (IGF1) or be diagnosed only to immunohistochemical study as is the case...

Introduction: Angiosarcoma is a highly malignant tumor, very rare and even more so when it comes to a thyroid localization. It is characterized morphologically by its vascular differentiation and cytological polymorphism. The objective of this study is to report a case of this entity with its evolution in the postoperative period.Observation: patient of 54-year-oldm, with no pathological history. Operated (total thyroidectomy) for compressive multihetero...

Introduction: Subcutaneous calcinosis are deposits of hydroxyapatite crystals in the skin. They are hard masses, poorly organized, located most often in the dermis or hypodermis. They are secondary to either local tissue alterations or the penetration of calcium salts into the skin, or to an abnormal phosphocalcic metabolism but which remains an exceptional complication in case of primary hyperparathyroidism. We report the case of a patient admitted to the endocrinology depart...

Introduction: Therapeutic education is one of the cornerstones in the management of various chronic diseases in children and adults. Several models of therapeutic education have been well developed (obesity, type 1 diabetes…); nevertheless, it remains less common and less developed in certain endocrine diseases. The purpose of this work is to present the therapeutic approach designed for children requiring treatment with growth hormone.Materials an...

Introduction: Hematological toxicity is considered as the main risk of synthetic antithyroid drugs; its major form consists of acute agranulocytosis which can be lethal and requires urgent and adequate management. We report the case of a patient who developed acute agranulocytosis within 1 month of therapy.Observation: A 24-year-old patient with no particular medical history was admitted for management of hyperthyroidism, with a history of weight loss, p...

Introduction: The discovery of a pheochromocytoma during pregnancy is very rare. The diagnostic and therapeutic approach determines the maternal and fetal prognosis. We present the case of a pheochromocytoma discovered during a pregnancy of 16 weeks of amenorrhea.Case report: Mrs. A.H 29 years old, primigravida, presented at 6 weeks of amenorrhea with hypertension, she was treated by alpha methyl dopa 500mg and nicardipne 20 mg; at 16 weeks she was hospi...

Introduction: The discovery of a pheochromocytoma during pregnancy is very rare. The diagnostic and therapeutic approach determines the maternal and fetal prognosis. We present the case of a pheochromocytoma discovered during a pregnancy of 16 weeks of amenorrhea.Case report: Mrs. A.H 29 years old, primigravida, presented at 6 weeks of amenorrhea with hypertension, she was treated by alpha methyl dopa 500mg and nicardipne 20mg; at 16 weeks she was hospit...

Introduction: When hypoglycemia is deep and repeated, it can induce various neurological disorders, including epileptic seizures. The link between hypoglycemia and epileptic phenomena is complex and poorly explained. We report 3 cases of epilepsy induced by repeated episodes of deep hypoglycemia.Cases report: Mr D.M, 48 years old, with a history of 3 episodes of hypoglycemic coma, admitted for status epilepticus with a blood glucose level of 0.4 g/l; cer...